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Glioblastoma multiforme (GBM)

One of the most "classic" forms of GBM is the "butterfly glioma" illustrated here. Approximately 75% of glioblastomas will "go deep", and infiltrate into and through the corpus callosum, spreading from one hemisphere into the other.
 

Admission scans after first seizure			One month later	Two months from original presentation

These images illustrate how one superficial GBM had an unusually early presentation as a small lesion. Because the tumor was a subcortical nodule, this mass caused and early presentation with seizures. The small ring-lesion had a rim of hemosiderin, and could mimic a benign process, such as an abscess or hematoma. However, an acute hematoma is usually not surrounded by vasogenic edema (as is seen surrounding this nodule), and an abscess usually does not have such a profound region of T2 shortening (hypointensity - the black rim).

After a few months, the lesion had increased in size. Then, dramatically changed its morphology to present as a more "typical" heterogeneous multiloculated and ring enhancing mass on both MR and CT.